Developmental Morphology 

 

2024

Genetic determinansts of micronucleus formation in vivo
Adams DJ, Barlas B, McIntyre RE, van der Weyden L, Barros A, Vicente JR, Karimpour N, Haider A, Ranzani M, Turner G, Thompson NA, Harle V, Olvera-Leon R, Robles-Espinoza CD, Speak AO, Geisler N, Weninger WJ, Geyer SH, Hewinson J, Karp NA, Sanger Mouse Genetics Project, Fu B, Yang R, Kozik Z, Choudhary J, Yu L, van Ruiten MS, Rowland BD, Lelliott CJ, Del Castillo Velasco-Herrera M, Verstraten R, Bruckner L, Henssen AG, Rooimans MA, de Lange J, Mohung TJ, Areds MJ, Kentistoud KA Coelho PA, Zhao Y, Zecchini H, Perry JRB, Jackson SP, Balmus G
Nature (2024) 627: 130-136

Effects of Tulp4 deficiency on murine embryonic development and adult phenotype
Jäger R, Geyer SH, Kavirayani A, Kiss MG, Waltenberger E, Rülicke T, Binder CJ, Weninger WJ, Kralovics R
Microsc Res Tech (2024), 87: 854-866

2022 & 23

Phenotyping mouse embryos
Geyer SH, Szumska D, Martins GG, Weninger WJ
Front Cell Dev Biol (2023) 11: 1284433

Detailed characterisations of the cranial nerve anatomy in E14.5 mouse embryos/fetuses and their use as a reference for diagnosing subtle, but potentially lethal malformations in mutants
Reissig LF, Geyer SH, Winkler V, Preineder E, Prin F, Wilson R, Galli A, Tudor C, White JK Mohun TJ, Weninger WJ
Front Cell Dev Biol (2022), 10: 1006620

The venous system of E14.5 mouse embryos - reference data and examples for diagnosing malformations in embryos with gene deletions
Geyer SH, Maurer-Gesek B, Reissig LF, Rose J, Prin F, Wilson R, Galli A, Tudor C, White JK, Mohun TJ, Weninger WJ
J Anat (2022), 240: 11-22 



2020 & 21

Smooth muscle specific ablation of CXCL12 in mice downregulates CXCR7 associated with defective coronary arteries and cardiac hypertrophy
Ghadge SK, Messner M, Seiringer H, Maurer T, Staggl S, Zeller T, Müller C, Bönigen D, Weninger WJ, Geyer SH, Sopper S, Krogsdam A. Pölzl G, Bauer A, Zaruba MM
Int J Mol Sci (2021) 22: 5908

Hypoglossal nerve abnormalities as biomarkers for central nervous system: Defects in mouse lines producing embryologically lethal offspring
Reissig LF, Moghaddam A, Prin F, Wilson R, Galli A, Tudor C, White JK, Geyer SH, Mohun TJ, Weninger WJ
Front Neuroanat (2021), 15:625716

Deciphering the mechanisms of developmental heart diseases: research from embryonic knockout mice
Fetal Therapy: Scientific basis and critical appraisal of clinical benefits, Kilby M, Johnson A, Oepkes D (Ed) 
Szumska D, Wilson R, Weninger W, Mohun T
Cambride University Press (2nd ed) (2020), pp 133-145


2018 & 19

Common and distinct transcriptional signatures of mammalian embryonic lethality
Collins JE, White RJ, Staudt N, Sealy IM, Packham I, Wali N, Tudor C, Mazzeo C, Green A, Siragher E, Ryder E, White JK; Papatheodoru I, Tang A, Füllgrabe A, Billis K. Geyer SH, Weninger WJ, Galli A, Hemberger M, Stemple DL, Robertson E, Schmith JC, Mohun T, Adams DJ, Busch-Nentwich EM
Nature Communications (2019), 10: 2792

Reissig LF, Herdina AN, Rose J, Maurer-Gesek B, Lane JL, Prin F, Wilson R, Hardman E, Galli A, Tudor C, Tuck E, Icoresi-Mazzeo C, White JC, Ryder E, Gleeson D, Adams DJ, Geyer SH, Mohun TJ, Weninger WJ
The Col4a2em1(IMPC)Wtsi mouse line - lessons from the deciphering the mechanisms of developmental disorders (DMDD) program
Biol Open (2019), 8 (8): online

A specific CNOT1 mutantion results in a novel syndrome of pancreatic agenesis and holoproscencephaly through impaired pancreatic and neurological development
DeFranco E, Watson RA, Weninger WJ, Wong CC, Flanagan SE, Caswell R, Green A, Tudor C, Lelliott CJ, Geyer SH, Maurer-Gesek B, Reissig LF, Lango AH, Caliebe A, Siebert R, Holterhus PM,  Beeb A, Prin F, Hilbrands R, Heimberg H, Ellard S, Hattersley AT, Barroso I
Am J Hum Genet (2019), 104: 985-989

Placental malformations are highly prevalent in embryonic lethal mouse mutants
Perez-Garcia V, Fineberg E, Wilson R, Murray A, Mazzeo CI, Tudor C, Sienerth A, White JK, Tuck E, Ryder EJ, Gleeson D, Siragher E, Wardle-Jones H, Staudt N, Wali N, Collins J, Geyer S, Busch-Netwich EM, Galli A, Smith JC, Robertson E, Adams DJ, Weninger WJ, Mohun T, Hemberger M
Nature (2018), 555: 463-468


 

2016 & 17

Morphology, topology and dimensions of the heart and arteries of genetically normal and mutant mouse embryo of stages S21-S23
Geyer SH, Reissig LF, Hüsemann M, Höfle C, Wilson R, Prin F, Szumska D, Galli A, Adams DJ, White J, Mohun TJ, Weninger WJ
J Anat (2017) 231: 600-614

Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout miceWilson E, Geyer SH, Reissig L, Rose J, Szumska D, Hardman E, Prin F, McGuire C, Ramirez-Solis R, White J, Galli A, Tudor C, Tuck E, Mazzeao C, Smith JC, Robertson E, Adams DJ, Mohun T, Weninger WJ
Wellcome Open Res (2016), 1: 1

High throughput discovery of novel developmental phenotypes
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A; International Mouse Phenotyping Consortium; Jackson Laboratory; Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource Center, MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bućan M, Murray SA.
Nature (2016), 537(7621): 508-514
 


2014 & 15

The embryogenesis of the equine femorotibial joint: the equine interzone
Jenner F, van Osch GJ, Weninger W, Geyer S, Stout T, van Weeren R, Brama P
Equine Vet J (2015), 47: 620-622


 
2012 & 13

A chick embryo with a yet unclassified type of cephalothoracopagus malformation and a hypothesis for explaining its genesis
Maurer B, Geyer SH, Weninger WJ
Anat Histol Embryol (2013) 42:191-200

Metric characterization of the aortic arch of early mouse fetuses and of a fetus featuring a double lumen aortic arch malformationGeyer SH, Weninger WJ
Ann Anat (2013) 195:175-182

Dimensions of the great introathoracic arteries of early mouse fetuses of the C47BL/6 strain
Geyer SH, Maurer B, Dirnbacher K, Weninger WJ
The Open Anatomy Journal (2012) 4: 1-6

HREM-data based measurements of the arteries of mouse embryos: evaluation of significance and reproducibliity under routine conditions
Geyer SH, Maurer B, Pötz L, Singh J, Weninger WJ
Cells Tissues Organs (2012) 195: 524-534

Some mice feature 5th pharyngeal arch arteries and double lumen aortic arch malformations
Geyer SH, Weninger WJ
Cells Tissues Organs (2012) 196: 90-98



2008 & 09

Measurements of the diameters of the great arteries and the smilunar valves of chick and mouse embryos
Weninger WJ, Maurer B, Zendron B, Dorfmeister K, Geyer SH
J Microsc (2009) 234: 173-190


2004 & 05

Cited2 is required both for heart morphogenesis and establishment of the left-right axis in mouse development
Weninger WJ, Lopes Floro K, Bennett MB, Withington SL, Preis JI, Martinez Barbera JP, Mohun TJ, Dunwoodie S
Development (2005) 132: 1337-1348



2002 & 03

Martinez Barbera JB, Rodriguez TA, Greene NDE, Weninger WJ, Simeone A, Copp AJ, Beddington RSP, Dunwoodie S
Folic acid prevents exencephaly in Cited2 deficient mice
Hum-Mol-Genet (2002) 11: 283-293



2000 & 01

Mohun TJ, Leong LM, Weninger WJ, Sparrow, DB
The morphology of heart development in Xenopus laevis
Dev Biol (2000) 218: 74-88